The most likely cause of the Football Manager 2021crash at startup is your antivirus software. Therefore, disable the software and try to play the game. If the works, you need to whitelist the game as you cannot have the antivirus disabled for long. Here are the steps to whitelist the game in the respective antivirus software. Windows Key + I > Update & Security > Windows Security > Virus & Threat Protection > Virus & threat protection settings > Manage settings > Exclusions > Add or remove exclusions > Add an exclusion.
Home > Settings > Additional > Threats and Exclusions > Exclusions > Specify Trusted Applications > Add. Home > Settings > Components > Web Shield > Exceptions > Set the exception. Locate Microsoft Visual C++ 2015 Redistributable.Press Windows + R and type appwiz.cpl, hit Enter.Home > Settings > General > Exclusions > Set the exclusion.
